is a highly potent and selective inhibitor of hypoxia-induced gene activation
M22 (15-30 μM
InChiKey: SHGAZHPCJJPHSC-YCNIQYBTSA-N
Chemical Name: (3S)-4-(6-amino-1-methyl-pyrazolo[3
Pimethixene maleate nic Acid is a highly potent andPimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5 HT2A, 5 HT2B, 5 HT2C, 5 HT1A, 5 HT1B, 5 HT6, 5 HT7, Adrenergic 1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4. 4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.