Q-VD-OPh hydrate - CAS# 1135695-98-5 o-13-carotenone C4H6O6/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18

C4H6O6/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18

Smiles: C[C@]12CCC/C(=C\C=C3\C[C@@H](O)C[C@H](O)C\3=C)/[C@@H]1CC[C@@H]2[C@H](C)CCCC(O)(C(F)(F)F)C(F)(F)F

Molecular Weight: 1981

PLK1 inhibition leads to pharmacodynamic pHisH3 modulation and significant antitumor activity in multiple DLBCL models

Q-VD-OPh hydrate - CAS# 1135695-98-5 o-13-carotenone C4H6O6/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18The broad spectrum caspase inhibitor, QVD OPh, provides a cost effective, non toxic, and highly specic means of apoptotic inhibition and provides new insight into the design of new inhibitors1. Actinomycin D rapidly induced apoptosis and this was dramatically inhibited by the caspase inhibitor, Q VD OPh (quinolyl valyl O methylaspartyl [ 2, 6 diuorophenoxy] methyl ketone). Q VD OPh was signicantly more effective in preventing apoptosis than the widely