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15-pentaoxo-1
exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM
and reduces pulmonary arterial wall thickening
an abietane-type diterpene metabolite
CSN5i-3 Catalog No.:M25384-C 15-pentaoxo-1CSN5i 3 is a potent, selective and orally available inhibitor of CSN5 Jab1, and inhibits CSN catalysed Cul1 deneddylation with an IC50 value of 5. 8 nM. Product information CAS Number: 2375740 98 8 Molecular Weight: 505. 56 Formula: C28H29F2N5O2 Chemical Name: 3 (difluoromethyl) N {6 [(5S,6S) 6 hydroxy 5H,6H,7H,8H,9H imidazo[1,5 a]azepin 5 yl] [1,1' biphenyl] 3 yl} 1 (propan 2 yl) 1H pyrazole 5 carboxamide Smiles:
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