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L-873724 ressin acetate 4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

SKU: 4968093809

4.3
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Description

4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Smiles: OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)N1C=CC(=O)NC1=O

Betaxolol hydrochloride acts on the heart and circulatory system and decreases cardiac contractility and rate

Chowdhury J

L-873724 ressin acetate 4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrileL 873724 is a potent, orally bioavailable, selective and reversible non basic cathepsin K inhibitor, with IC50s of 0. 2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively. L 873724 also exhibits an IC50 of 0. 5 nM for rabbit cathepsin K. L 873724 inhibits bone resorption. Product information CAS Number: 603139 12 4 Molecular Weight: 481. 53 Formula: C23H26F3N3O3S Chemical Name: (2S) N (cyanomethyl) 4 methyl 2

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