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3-dihydrobenzo(b)(1
Chemical Name: 3-((6-(4
InChi: InChI=1S/C21H15ClF4N4O3
p) significantly reverses formalin-induced impaired hippocampal-dependent behavior
RAF265 enafil dihydrochloride 3-dihydrobenzo(b)(1CHIR 265 is an orally bioavailable small molecule with potential antineoplastic activity. CHIR 265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR 2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras Raf MEK ERK signaling pathway and are frequently
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