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52 μM (A375)
Smiles: O=C(C1C=C2C=CN(C2=CC=1)C1C=CC(F)=CC=1)N1CC(C1)N1CCN(CC1)C(=O)C1=NC=CS1
Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors
7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain
AZD5718 14821 52 μM (A375)AZD5718 is an orally active inhibitor of FLAP (5Lipoxygenase activating protein), with an IC50 of 2 nM. AZD5718 is used in the study for coronary artery disease. Product information CAS Number: 2041075 86 7 Molecular Weight: 446. 50 Formula: C24H26N6O3 Chemical Name: (1R,2R) 2 [4 (5 methyl 1H pyrazol 3 yl)benzoyl] N {4 oxo 4H,5H,6H,7H pyrazolo[1,5 a]pyrazin 3 yl}cyclohexane 1 carboxamide Smiles: