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Chemical Name: (Z)-3-(3-nitroanilino)-1-phenylprop-2-en-1-one
PubMed PMID: 24900311
4 mg/kg MK-8776 S-isomer is sufficient to induce the γ-H2AX biomarker while 8 mg/kg leads to enhanced tumor pharmacodynamic and regression responses relative to gemcitabine or MK-8776 S-isomer alone
and the bioavailability is 40%
Medicarpin - CAS# 32383-76-9 Catalog No.:M12563-10 Chemical Name: (Z)-3-(3-nitroanilino)-1-phenylprop-2-en-1-oneMedicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P gp mediated efflux of drugs. Product information CAS Number: 32383 76 9 Molecular Weight: 270. 28 Formula: C16H14O4 Chemical Name: (1R, 10R) 14 methoxy 8, 17 dioxatetracyclo[8. 7. 0. 0, . 0, ]heptadeca 2, 4, 6, 11, 13, 15 hexaen 5 ol Smiles: COC1=CC2O[C@@H]3[C@@H](COC4=CC(O)=CC=C43)C=2C=C1