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GSK650394 is relatively non-toxic
ZT-12-037-01 60110 GSK650394 is relatively non-toxicZT 12 037 01 is a STK19 targeted inhibitor with a high affinity interaction with STK19 protein and inhibits oncogenic NRAS driven melanocyte malignant transformation. It inhibited phosphorylation of NRAS (major isoform of Ras family) with IC50 value of 24nM. Product information CAS Number: 2328073 61 4 Molecular Weight: 385. 50 Formula: C21H31N5O2 Chemical Name: N2 cyclopropyl N4 (1 isopropylpiperidin 4 yl) 6,7 dimethoxyquinazoline 2,4 diamine Smiles:
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